#Calcineurin-CE+iThymidylate-synthase Consensus 90% ...................................................................._..._hlphoD_Hh____...................p_______h___hp_l___h.._______hhhsGDh_____.................___a.__h___h.__h_.______.._.ph_hsPGNHDl_____..............._pa__h___..............................____.__h_....____h_lh_hNos__......................................................___p_s_ls___h______.................___hhhhHHpl_s..........._____p...._sl_s___hb__l____h__hhHGHpH_____............___.pp__llusss____......._____phl_____..........._h__h___________.........h____........._______h_u_s_p_ha_ph_________....___h_h_h_............._____.______a_.._......................p_h__Wp___..___...___a_HGpbh.................p_hp_h_p_L_...._.__osRulh_Llp___s__........____hsuhs_hph____..............._l_h___hR_bEh__ah_lNhsEl__h___h__..._h......_____pls__s__s__.._p__sph_._s_lD___p_......_h__h_......................._______h___l_pb______........_.l___Gh__h_phh_____........_..___....h______l__________....__________....__________h_________....................................... Consensus 80% ...................................................................._..._llploD_Hls___...................p__pbpp_h___hp_l_p_l..____b__lhhsGDh__psp................._s_a.__h__hl.__h_.______.._.pl_hsPGNHDl_____..............__ca__Fhp__...........................______.__l_...____ph_lh_lNSs_a......................................................_p_chupls__plp_h___h...............___plhhhHHplbs..........._s__-p....psl_Nh_bhbp_l_p__h_hllHGHpH_____............___.cchbllusssh____......____hpllph___..........._l_ph_______s___.........a____........._______h_upshpchY_ph_________....___l_hplp.............p____.__h___a_.._......................phh_hWQ__p..___..._h_asHGpbh...............__s_hp_hhp_L_....p._sooRAlh_Lls__ps___......._p__hsuhsblQh____..........._____L_h__ahR_bEhp_ah_lNlsEl__h___l_p..._h......_h___pls_hs__h_h.._p__sph_._s_lDph_cp......pl__hh......................._p___p_h_p_l_-b____ps........s.ls__Gl__l_phl_____......__p.____....l_p_h_pl_p____h___...._p_______h....___h___h_pl__________...................................... Consensus 70% ...................................................................M_...blLploDhHls_s__..................sbpsppp_hpp_hc_lsp_l..p__pbshllhsGDh__pup................._sua.p_h__hl.p_l_.s___s_.._.pllhhPGNHDlsb_s_............s__p+appFhp__................p._........___ssp___l_...___psh_ll_lNSspa......................................................_p_-hu+ls_ppLc_h_p_h__............._p_plhhhHHpLbs..........._s_p-c....pslpNh_blbphlpp_pl_hllHGHpH____h............s___+chhlluuush____......_ss_hpllplps_...........plppl_s___s_sh___._.___..ap__s........______shhpGsshsclYpplhp_hp_ps_....__sl_hplp.............s_psh._shspsas.._.__.____.........___h_clh_hWQ__p..hsp..._h_asHGpph...............__s_lcbhhp_L_....pp_sooRAlhsLlcs_psh__......._s__hPuFshlQh_hpp..........._sppbL_hssahR_bEhp_aa_INluEl_blbbpl_p...pl......shp_spIsshu_bAbh.._cp_sph_._s_lDph_-p......plh_lh__h__.................__pp_hp_h_phLp-b___sps........s.ls_pGlppL_phlp_hp_......__p.___p....lhp_lppl_p__p_h___....ppp___bpph....___h___h_plbp__p_____...................................... Consensus 60% ...................................................................Ms...bILaloDhHlssss_._____D_.K__._.___-bpocpphlcp_lcplsppl..pppclsulllsGDlsspus................._sGa.pph_sll.s_l_.shh_s_..p.pllhlPGNHDVspss_...........sss_cRYpsFlphh..___._h__shh-s_D_____.....___ssp_p_l_..._pssshsllslNSupas____________..........._l____..............__h___h__bbpaDhu+lu_pQLc_hbpbl_p_____........ppl+IhlhHHpLhs...........ss_p-Ehps_puIsNL_plpshLccpplshVLHGHKHs__hh_-___.__....s_s_++hhVluuGshbps_......sss_hpllplpss....._____lplpplss_phusshpp_.s._____ap_ps.......____sssshlpGsshs-VYpclhs_hp_pss...._bsLlhcls.............c_ssh._slPpsas..h___.____.........p_Wh_-lhpWWQpsc..lsp...sl_asHGpRl____s..........pbsQlc+lhc_Lp....pp_sSSRAlhsLl-sppshps.......scsbaPSFhhlQF_hps_..........sspppLchsuYaRsQEhpaWWsINluElhhlppplhc...pl_.....shpsGpIsoluhcAph..pcshsphh.hs_lDRh_-p.__...pLhbLh__h____...............__pchhppW_phLc-b_ssscs......__s.ls_cGLcpL_phlpshss......ppp___sp....lhp_LppLhpb_pphppp..__sps_pshcpa...._p_lpp_hpclbphhpphb____.................................... Consensus 50% ...................................................................Mh...hILHLSDLHLussss.____sD_.K_p.h.s__-pcoccchlcchLEpLuccL._cppcLsullloGDlsc+Gs.................ssGa.cchpclL.cpLs.chhscb..s.+IlhVPGNHDVs+ssh...........Puo_-RYcsFlsha..+p_.Gh_TPhLDGlD_s___....._shssspahlh...sc-ccahllslNSSsas_sp__h__sh__._h_......._l____..........__.___l_p_lpclpsaDhARlSpcQLchlpphlpps__s_........spLRIhVlHHpLhu...........huscEEhKsFsuIoNLuplRcaLccpclclVLHGHKHspshhaD_h__s_....shss+RhhVISuGolbsss...._pssshh+LIclsus.....s_s_plplpslsshphuh-hcp_.s_b__p_Wpbps......._sssssssllpGsols-VYc+llchhpscus....lbsLlhclc.............D_suh_bclPpsYPp.l__s._sss.........p_Whp-lVsWWQpscs_lsc...slsFNHGpRlb_a_G........._chDQI-+llchLp....scsoSSRAllsLlDPpcDhss_......scspFPSFhllQFshps_..........ss+pcLDlluYaRAQEhsaWWPINlAELhhLQpclhc...cl_.....slpsGcITTlAucAph..scshspVu.lPpIDRhhDp.P_...cLhpLh__lsssp_............___pcchlspWpchLcDhpshu-s...s_cu_P.VshcGLcpLhchLcuhss......csc_phsc....LhssLcpLhcphcphcps..__spsssshcpa....ppslpshlscLhphlsshhs____................................... annotation **************************************************************************************************************************************************************************************************************************************|Calcineurin|*************************************************************************************************************************************************************************************************************************************** *****************************************************************************************************************************|inactive TS|********************************************************************************************************************************** *******************************************************************************|Helical Domain|****************************************************************************** ss_from:RGG55697.1_A ------------------------------------------------------------------------EEEEE----E-CC---------------------HHHHHHHHHHHHHHHHHC----CC--EEEEEEC--ECCC------------------HHHHHCHHHHHH-HHHH-HHCCCC---EEEEEE--CCCCCCC-H---------------HHHHHHHCCC--------------------CC-------CCC--CEEE---EE-CCCEEEEE-CECC------------------------------------------------------C-CCCEE--HHHHHHHHCC-----------------C-EEEEECC-CC------------CCCC-------CECCHHHHHHHHHCCCEEEEEE---CC--EE------------EEC-CCEEEEE---CCC-E----CCE--EEEEEEEECC-----------EEEEEEEEEEECCCCE---------EEEEE-------EEE-----EEEEC-HHHHHHHHHHHHHHHCE----EEEEEEEEE------------EEHHHHHHHHHHHCHHHH----------------------HHHHHHC-CC----C---CEC--CCCCC------------EECCEEHHHHHHHHHH----H-CC-CC-EEE-C-HHHHH-C-------C-----CEEEEEEEECC-----------CC--EEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHH---H-C-----C--EEEEEEEEEEEE----CCC-E-E---HHHHC-HH------HHHHHH-----------------------HCC-HHHHHHHHHHHHHH-EC--------C----HHHHHHHHHHHHCCC------------HH----HHHHHHHHHHHHHHHHHHH-HH---HHHHHHH----HHHHHHHHHHHHHHHHCCC---------------------------------------- RGG55697.1 --------------------------------------------------------------------M---KVIQISDLHIDSHF-------------------MLSNYQDMLNKMLECIRNDM--VDEERIYILCCGDIVNKGN-----------------ADEYIGKAKAFF-DFII-DNMKGK--EIELLFVPGNHDLCASSF---------------DKFQSFIEQY-------------------NGK-----INFISE-NVIL---YEGTEINFVLVNSCYH------------------------------------------------------KDYQYGNIDIGAFKEVIMKL---------------FKPSLVVMHHTLLS-----------RYSDDR----SAISNAYKFLDILENSNVIGVLHGHTHGYSNI------------LVG-ENCRIIGVGSLFTYI----PNCNNQFNIIDVKLG-----------KVERVINYRYNFDLEK---------FSKVI-------LFENLKRNFFTDNKISTVYSKVKDTVKYYGG----INSLSINVN------------TTIDEYKYDMEKNFEADI----------------------DIAKLWLKEE--VPS---TLYYNHGQYM------------VDSRNKGINYIIDELV----RNSTSNRAIIPLVRFSDVLDK-------QFGHLPGLNSIQFGFLN-----------DEKADLFCSVYLRSLEVNHFFKINLSEIYLLLMQIFN---EIR-----SVKRLIINIYAFKAQY--KEKFSCFR-KAKIDTLNVG------TLSKFV-----------------------YQRDILEIVSLLRDKFDMEET--------V-INTTGLTNFYDILKASEL----------YNEK----IISGLSEIIREMENLKQEY-MKSSNYEEIKPI----EERIHKKQERYIELVSNIEA--------------------------------------- MBX3099580.1 -------------------------------------------------------------------MA---TILHLTDLHLSQPSA-ATAIGDYSKAQ-LLDPEEFQSRKTVLEASLESLGDYLVTQHIELDSIIITGDITVTAD-----------------PGGY-ALLPSFL-AKLG-AAMVEP--D-RVLLTPGNHDVRWSAA-----------PGSVERYESLLELR--TQT-GYQTAYFDGIDIDNAGR----PRGATVNPLLE---AGDGSYIAVGLNSSNHCGVDAAVEVELAD-RLD-------AIVKKA--------GRDKDVAALLQAWKRRGLSDLARVDQGQLIAAGNLWAEPASAA--------TPLRIAALHHQIGP-----------VTAVEELKAFETMSNLGAFRTWLLDHSVDVVLHGHTHVAYNRHDIQRSYHSTLTASAEHRFLVVGGGTVERGS-----ADAILANLIKTAPT----APRLWPVSVGGLRATLTKKPLNAG-D-FVVEDVFVR--------GDLEHTVGVVAGANVNEVFEQLLGLGDLSGS----ARPLVCRIA-------------DGASA-LRLPTSYPD-SPFP-ADIA---------ESWLADTVGWWQRAP--RGL---GASFNHGERLKYRDG---------EEFDQIERAACALA----KDTGSSRGVAVLVHPRTDLV--------DDAAFPSFVMLHATVTGF----------GSRKQLDLVAYFRKQEIPHWWPVNMAELATIQETMID---IMAANARPGVRPGSLTSVTSIPVV--GEGIPFVS-VPWIDRSADN-PG---ALLSLVTPLLVGD----------------ATGAETTWEVALGDWALGDQP---PADGEP-IPLEGIQALIVLLDGLSEAFGP--TREATLRV----LVKSLKTISHENASYRAA-LHGKKRAEARIRW----VRAVNEERTILRSAVVELVRALVP----------------------------------- WP_181277705.1 -------------------------------------------------------------------MSNSVQLLHITDSHIFLGGG-DYHPYDK-KLD-L--SIDDHSREEAFQLLIKRIAEVMRSRGETLDGVIFSGDALLRGK-----------------PGGN-HALLDLVMQRFD----LAA--N-RILAVPGNHDVPRGVA-----------PGSEERYRDFISVW--RSA-GCITPWLDGVDAGP-------EAADCSRHVLT---AADHSWAVLAINSCNWSHVDAVVPDALRE-VWD-------HLPAAA------TSKGEDAQEAIKKALNDLLRHDAAHISRAQFERIRDMFERLPKPEYG------RQLRMVALHHHLRN-----------PSMRLEFKTTPDLFPLEALRAQLRELDVRVVFHGHKHVSRQYFDYIESRVAP--DAPPRRTLVLSGGTFSDND------AGDAASCARFEGL-----PWTPSVRVSTFAVPQAGLPLETK-ESSELRLWEYAD-------STPGGNLALIKGTDLDEVYAKVRACAGGDAK----GLPLVVELDLA-----------ANEPV-GVLPHGYP--TIAA---EQ-------ERDGWLRDLVEWWQRRDSQLQG---RIPYIHGNRLLKYSG----------NIDQMARVTKLLQ----D-RNTSRAIAMLVDPRLDFIEEP-----KRREFASFCMVQFVRRPDP--------KGGLPFIDAIGYYRAQEMTQWWPINVAELRHLQLQIIH--GGV------RARAGRITTMTADARADDAPSPTHAA-MPLVDRWLDQAPE---KFFVLASSMQAGKL------------EGKGEAVGREWLDELKTLQQSAHR--PAHDGGPVVAIDGLDRLAAYLRAGSG------GSGGTCGE----LANVLDELARHAEKR-------PDDPKAAESW----LRVMESCLTRATELSQKALGAELPR---------------------------------- WP_096477646.1 -------------------------------------------------------------------MA---LLLHLTDLHLGAGGA-DKSTADE-KVK-VIPPHEMDTRLSDTVRLVERVIEKL--KGDRLSSIVISGDITVGNK-----------------LDGY-NRLNDFI-GRLS-PLLPAE--KGAVIAVPGNHDVAWGTE-----------ASSVERYRNFKQFV--RDDLKATTPFLDGVDTLQKGKV---KLVGAKKAYFA---NKEHGYAVVPLNTSNYCGSNLLIEGVTQP-DIE------LFLEQAK---------GLRNGEAIVRSLERLTRFDIARVSPDQISAFEISVKSARQELKDSTD---SALIISTFHHNLAP-----------VSRYEEIKAFETLTNLGRLQETFTDLGVKIALHGHKHQPMAYWD----NRQIV-GGKATEMLVLSGASVGGEG----YSAEVPFQLIEVNRV-----DGGHDVQVHSAKDFIGDKPAFVR-MGLIHGNWKKPV--------SATDRSTIIEADTFDKVHEAVRNLPLFEDGFNHPLNNVVTTIR-------------DGNSVTKRVPIGYPKDV----VDDP------NTVDNWFDEIAGWWQTDLSELSS---DLYFTHGTRIKRYRG----------IVNQLEHAADVLK---SPDPRNGRAIITLIDPESDFRSGNNKK--RGGWFPAFSMAQAYITNE----------DGKNKLNIVGFYRKQEMRYWWAVNIRELRLMVDMLAR---RV------KASIGSITTVATIAIA--DGGKPRVA-VPVLDRWYDKDKG---KIAQLVLSAVNSSR--------LDQGNEADHEKLALWRAIIADLVPVELPDGAAVENVP-LATKGLELAHELLKAFSEF-----ESSPRLSA----LTECLARIQTECASIVQTV-LQKNTSAAYEEYDRS-RKLIAIQAQEARTVLQEIFHV-------------------------------------N WP_108507490.1 --------------------------------------------------------------------M---YILQLSDLHIGIDI-------------------DLDEFKSKIDKIYEEVNKII--EKSELLIFCICGDVTDKGN-----------------KDGY-KNATIVI-DYLK-EKFTDY--NHKLEFIPGNHDICEEKF---------------EEFDKFIAGY------------------IDEK-----YSYEDK-NVVV---RNYGDINLVLLNSSYH------------------------------------------------------KNHEYGKIDLVQLRSELKE----------------NENNFVIMHHTFIS-----------EYDDDK----SAIRNAYIFIKALDENNVCALLHGHTHGYSDI------------SIS-KECKDIGAGPLFKKL----EDINNQFNIIEIKAG-----------KVNRVYNMRYSSDLGT---------YSVID-------VYSRKNLNNFYGNSLIEVYNDVVESTREHGA----IINFNMNIR------------SDLNTFNNDVQTIFHNQI----------------------NIAEEWQEET--PPS---TLYYNHGQYM------------FKGKVDPIEYVINELK----DKATSSRAIIPLINMEDVVGS-------GDNFLPSLDIIQFGFKE-----------DNKEELYVTLYLRALEVNNFLKINLSEVYVMCKKIRE---RIR-----EISILNITIFSFKAQY--REKYSCFR-KADIDMIDES------DLMMSV-----------------------VEKDINTIISLLENKHELSET--------V-VHLDGVEKLERCIKNYNK------RKKEVYSE----DICN------------------------------------------------------------------------------------------- MBD5099121.1 -------------------------------------------------------------------MF---YIVQMADFHFGGSHL------------------GSESEKDILKKMAERIQAEI--PSDAEVVFCACGDYIDSKPVSDGTSTGTRDLTDAEVESRY-EEAKDALMSTVIDPLKKKYKYKFKVGLCVGNHDTTHIDA--------------VNRFSQAIAS----------------------------TDIDKT-YSLH---LDSENVDLIFINSCPP------------------------------------------------------SDFSHGQIDYDYLENTLKTLPA-------------DSTKYFILHHTLMS-----------MDERDQ----SSIRQVPKLIELINQYAVKAVFHGHTHGQYMI------------RIGTEGCPIISVGAAYVRDF---PNVNSQFNLIRCNSG-----------IPISADNYQYHADWAMN-PGTDG--FEKIS-------IPISKENNYFYGTTFSRVYDELTKKVRAESK----LYHVNLHVK------------SRFDQFCSDVTENFGKKVELK-TFDK---------EYSYTELAEMWQDSE--LDE--KVLYFNHGKNF-----------CTKQHQSGIDYIIHELS----QKMTSSRAVLVTVNSKDISQTA------PDALLPSLLSIQVGFD------------RDMTTLHITMNLRALEANRFLKINICEILFLAQKIHE---TY------PFQNIEVAVSAFRVQI--KEQFGCFL-KAKLDTLAQS------NEMAIT--LACLRYSND---------PTVITGQIEYVIRLIRDKKLRSET--------V-IVTAGVENLLNSIMDVKNGMPA--GKETLLSK-LDQVCTYTKNLLDMLNELKKRRASHSEPTEDMDAL----EEDIEHQYDLLIEGFERLKEP-------------------------------------- MBS1892551.1 MT--------------------------------------------------------------PQSMT---SILHLSDLHLGPPDS-WQRVDDD-KYD-S-SKIDSRTQKTILSQAIEKLVAER-ERFDPIAAVVISGDLVLGKHA----------------DLGF-EEFTDFV-KPLT-DLVRPD----RVIVVPGNHDVPKEVR-----------PSESGRYDAFLKVT--RHQ-GFVTPLLDGIDFSESGT----PTVDPQARHLA---SHEDEFVIVPVNSSHFCWGLHPLEDEAVE----------RALRRAK--------------KNDKKAVERLLHHDIPRISNAQMRAIHQFARVRDPDLLEPHE-KDGRLRIAVLHHHLLP-----------VSSREEFTSFESLTNLGAVRLFLAQMEIDLVLHGHKHETALYWDYVA-NEQGL-DAKPHRMLVSAAPGDFRP-------RRPALRVIRVEGT-----PLAREVVIEDIMGPSAVVGALDT-DRKRARIWRDTD-------PDRVGDATVVRDQTRDGVYEKLLSLFADRAIG-NPLRDLVCEIEEA----------VDIESL-MKPPNAYP--VMKR-VADP---------EKWMEDLVNWWQLKDPQLLS---QVTFNHGNRIYSRFG------------DQVQKAAAALATADGSPTSSTRAFISLVDPRSDGG--------RTGEFPSFVSVHLQLVND----------SSTQRLDCTGYFRKQEMRYWWPINVAELALVREAVER---EIRKRGL-ITRQGRLRTISSYAAA--GRHLPTVA-LASIDRAVDQHPK---DLWEMAHGVARQGE-------------GDSAAVRQTWERYLDDLDPPDEP----EPVIQ-LSYQGLRRVYEMLGWLGGA-------ESEAGKALDRLAHFYAQLVEQRSA------SGEQVGANATTY-----------LGELREALDKILGQAE------------------------------------ RYY28726.1 MKPINHEIMKMARYCEDALRESNPLETSPWVAADISSVRKSAAILDTMRSTCPIVIELMLGYVAD--MT-APLFLHITDPHITGEGV-PLERDDF-KIK-I-PKIEHGSREAALDLLLSRLAEQLQSEQRELDGVIFSGDAAERGK-----------------LSGH-AALRDIILNRLG-NVGVSP--A-NIVATPGNHDVPRTTA-----------PSSAERYEAFIGAW--RNA-GCKTPWLDGIDDI--------TRLDPDQHRLL---GADNSWVIYPINSANWSHATSELEPPLSE-IWE-------KIPKLL------GDGHPD-AAKLANQLQSLIRYDMARVSDEQLEAFRTIVSSTPPATLG------SQLRLAAIHHHLRA-----------PSLHEEVKPFADFTNLELLRQTLRERMIDVVLHGHKHQHAVQPELIYDTD----GLNPRRVMIISGASFDGRK------EADAVRLIGLGKL-----PWTPEIELTRVALPRAGTELKSK-LESPISLWRPLE---------PSSGSITIQGSDLDDVYHRAVELASGEAK----GTTLVVDLDLP-------------AASHAGIPVNYP--APQS-LDAP-------GRVQWFDELAGWWQERHSRLEE---RVPYHHGSRLHRYAG----------VFDQVDRVRKLIE----R-KASSRAIAILIDPLRDFMPDAD----DAENFASFCLVQFRKRDIG---------EDKSAIDVVGYYRAQEFLRWWPINISELRALQLAVCD---GK------KRVPGRISTITSEARA-IGRSPTEVS-VPVIDRWLDQHPG---RLFLLATYLTCGKV----------ENEATRDDVVSGWTQSLEDFEFAAEH--FNEDGVP-LAIDGLATLMCYIEALKP------SGQ--LRE----FVDALDALRKANIAYLGT----KQRSKDFDNW------GALPHIRQLRKLSAALLDEQVSA---------------------------------I TSE03211.1 MGLVCRSRIRCRL-----------------------AGRDHEAPSATRRTSIP--------HPPPSPMT-PPRFLLITDTHLADGGS-ELRLDDLSKTT-I-PSISHPTREGEIGKLFERIASDLRGKEQRLDGVLFAGDAQRKGL-----------------PGGH-KILFDLILANFG-EFGIEP--G-RIVAAPGNHDVKKWSE-----------PSSRERYEAFAAVW--KAN-GCIVPWLDGVDSR--------NSVDASKHFLA---AHDNRWIVYPLNTSNWSQVQAELPKDLAT-IWN-------EIPARL------S-ANAAEQERLSSALNGLRSYDMAHVSDAQLEVMRGVIASAPRPESG------PQLRVLLMHHHLRA-----------PGLRVELKAFESISNLEQIRSFIRQAEINLVIHGHKHEHAVHFDHLGGER----VEEGRRVAVLSAGAIDDGR------DTDAARILAIEGI-----PYTPTLQSTRFGLARGGLNAPME-VEKPIRLWMMTS---------LADGPEIIQGSDFNEVYARASDAAREIVP----RGTLIVHLDLP------------ANSVQLDLPEGYP--EAAS-ISVP-------ERQQWLREIVDWWQLPQSHRDK---SFPYPHGSRLRRYGG----------VSDQIERLATMLESGRSSPTLSSRALAILVDPIRDFDAGS-----EREAFPSFTMLQIKKRQR----------SNTTLLDITGFYRAQEFSQWWPVNIAELRAIQVKLCR---RV------GIEPGRITTITTEARL-DERAPGQVH-VPIFDRWLDQAPQ---NLFLLAGILSQQIH-----------EHPNAKDLLGQWRQALRDFLVVAQA--RSTDGSP-ISSEGLKALRDYIAALCP------ADR-PRPQ----FFSSFVSLVEQSEQFERS----AKDTSSFEIW----ARVVKRVVPEILNATTS----DGP----------------------------------- WP_209049350.1 -------------------------------------------------------------------MA---LILHLSDLHLTELNT-SDVVADV-KDDGVVGIGDQQTRLDIIRGSLHALGAWLRRDKRTLDSIVISGDIAQQGD-----------------PRGF-ALLPEVL-GELG-DKMPSS--N-RVLIVPGNHDVKRGSK-----------PSTPERYAEFSTL---AKH-GYLLARMEGVTLAEQ------TGAPDTDPIIT---ATDDSYVVVGLNSSNFCQEPRDVPGTVAG-AVE-------RLRERD---------GDEDAEQLLAAWSALQIVDIARVGSEQLRLGSELLQRSTQDQAAGGQ---LPLRIVTMHHHVQP-----------VGANEEIKGFDNLVNLGEFRDWLVDNDVDVVLHGHKHIGSIAVDTHMPSHRP--GSRPHPTLLVSAPSVQSNA----SGRDDVGYLVDVPGP----AARWSGVRIAPLSPHGPGGGRFEP-A------FKRHA-------IRPEPKLGVLEGCSLTDVHRQVLAVQDQLDEL---RWPLVCTVI-------------DGSTG-LRPPSTML--LPDG-VGNA---------AEWFDDIVAWWQTAGASDAS----RKFTHGDRLRRFGG---------VPIDQIKHIVRALR----SDEKTTRAVAVLVDPTRDFDPA------NSNRFPAFSLIQFQVKND--------------KLDAVAHFRKQEMPHWWPINVGEIAKLQAEVLA---AL-GRGR-GLRAGRITTVTAMPVA--GDAFPTVA-VPRIDRITDD-PG---AMLELVLPLISGT---------------ETAVALERWRDVFADWQPTDAA--PAADGNA-VPLRGLATLADLIRGVVDAG---LDVRGQLDE----LANALDDLQRLARQGDDSA---TRRSEPFDRW----ASLVVQKIADVLARVEACFKASASG------APNSEGVTG-----------GR---L-- WP_216172683.1 --------------------------------------------------------------------M---KIVQMSDLHITENI-------------------DIRYYKNKIDKLYHVLCEEI--KQDEEIIFCICGDIIDGGK-----------------EASY-DNAEIIF-DYLT-SKFQDY--RCNYEFTPGNHDLCNNDF---------------RGFDKFIRKY-----------------LKGDK-----YEYQKQ-DVII---RKYDDVDLILVNSIFH------------------------------------------------------KDFTYGAINMENLKEALREC---------------NKGIIIVTHHTLMS-----------RYQDDK----SSIRNSYEFINSIQGKGVCGLLHGHTHGYSNI------------TIG-DMCKVVGVGPLFKEI----KDINNQFNIIDILAE-----------KIDEITNFRYSADFNK---------YNKIQ-------VYKRKNMNIFQGTKTSEQYLSALETTKQYGC----INNFNMKIT------------TSCEDFFSDMQKTFLPDI----------------------EIAKQWQALE--LPE---TLYYNHGQYM------------QKDGIDGIKHIIKELQ----SKATSSRAIIPLIDIKNVIGS-------GDNFLPSLDIIQFGFNT-----------EDRTELYVTLYLRALEVQHFLRINLSEIYVMVKRLKE---EIR-----SINKLNINVFAFKAQC--KEQFGCFK-KAKIDILEER------NIMRMV-----------------------DKKQISEIYSMLKEKLELSAT--------V-VNVKGIINLYNCIIEFEK------DESFFSPS----LLDNIQNLINSMKLLEQLR-TKTSNYIEIKEH----EKKVEHNMVFVIKQFETLKGGS------------------------------------- WP_101303253.1 MVSKINSILPNI--CEEVLK---------YIKITICVIGNKNFHKKV------------I-------YM---QIIQISDMHITEDS-------------------NLDLIKDKIRKLYIALKETL--TNVDQTVLCILGDIVDKGN-----------------AKLY-KKASDIL-YYMK-EIFEEF--NPTFEFTPGNHDLCNCPYSHPIPEKCPDTKCTLEHYNNFVKNF------------------DSS--------YDHTYTLLR---KEYDDVDLLLANSVHH------------------------------------------------------GNCKYGLLDFEALRMIELQ-----------------KPTLLVTHHTFLS-----------ESDTDI----APIRNAYKLFDEIEKKEIIGVLHGHTHGYKDI------------TIG-NKCRVIGVGPFLKDI----PNINNQANLVTVTPS-----------GIQKVLNYFYRSDLDQ---------YVSRS-------VYTRDN-SLYKGSNIEKLYYEIVSDAKNTGV----IPNFHLNIN------------MSFKEFNDEIERIFHEDI----------------------NTAKMWQDTE-QVPE---SLYYNHGQYM------------KYNNITAIDFIIKELK----SKATSSRAIIPLINFEMVVKS-------GDGFLPSFDLVQFGFLA-----------EDRTHLLATLYLRALEVRHFLKINLCEIYLMCKQIAD---EIR-----SIERININIFAFKAQY--KETFGCFK-RAEIDRIDES------EIVL-L-----------------------LKEDLKSIVHLLEEKRDLNET--------V-IENKGMTSFFKALQAINK------RRT-IKTE----ILQQAKSILDIMEKLKSER-EKTSNYTLIHQI----ESQVNEQFNKIIEMLREGDIYEY------------------------------------ WP_164743577.1 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WP_081690911.1 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WP_135545199.1 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WP_019229254.1 --------------------------------------------------------------------M---KIIQISDLHINCDT-------------------DLGRIEYKLKKMYLAIKDDL--KTQEEVICCILGDIVDQGD-----------------ATMF-EKAETIL-GYIK-DLYKDY--IFSFEFVPGNHDLCYGTL---------------NDYDKLISKF------------------TTSP-----YTFNSQENIYV---REYNEISLILLNSIYH------------------------------------------------------KSHEFGKIDISSLSEIACE-----------------KPSIFVVHHALMS-----------ENDDDK----SSIRNAYKLIDEIEKRDALAILHGHTHGYKNI------------KIG-QRCLVIGVGPMFKPV----EDINNQFNLIDIRGT-----------IIQSITNYRFSNDLDS---------YNSIL-------EYEKPQTNNYYGHSLQKVYDNIVEDTKNYGF----LMNLKFECT------------MTFESFEKSILEHFNDSL----------------------ELAKDWNSPE--LPD---NLYYNHGQYM------------KYKDKWGTDYIIEELN----NKATSSRAIIPLINFSNVVNS-------NDNFLPSFDIIQFGFEN-----------ENRNNLIVSLYMRALEVNHFLKINLCEIYIMAKDILD---SIR-----TINNISINVLAFRAQF--KEKYGCFK-KSKIDIMTEA------QLTKLV-----------------------LNNNKSEIVKLLKDKVESSET--------V-IQNEGLLHLKNAIAEADG------YKT---------IMDMLIIVLDKLDVLKRER-SRTSNYLEIKKY----EDELSNAMQNLMLNLEGDKYI-------------------------------------- WP_198876784.1 -------------------------------------------------------------------MASSATFLHLTDTHLRAATT-ELRTRDI-KTA-L-PGVTQDTREAAVDRLLAMVAERLESTNQKLDGVLFSGDAQFRGE-----------------DGGH-AELLAAILKHLA-PHGVSR--G-NIVATPGNHDVPRKSP-----------PSSAIRYKAFLEAW--GAE-GCVIPWLDGDH----------ESNGRNPHVLE---ATDKSWKIVPINSSNWCQTEVSFPDELAT-IWD-------RLPVLA------APADDQLQEKLARQLDALRVHDVPRVSPEQLEALRTMLRSDLSSP--------RQLRIAMMHHHLRA-----------PSLREELKTFESITNQEHVRTFLREQDFVALLHGHKHETALTYEDIYADG----EDVPHRLAVISGATFDNSQ------HRDAMRLVHLKGL-----PHNPSVEVEMLSVTAQGLEPDWS-ACVSLKLSQPRH---------DESAPVMITGTDITEVYERVVEAASGKAA----GGIIIADLDLN-------------PDVRLPLPEGFP--LTSE-MPGE-------DRTKWLQDIVAWWQLPNPKNVV---TFPFPHGSRLRNYNG----------NFDQLNRIISLLK----D-KPTSRAIATLIDPARDFSETG-----TGEVFASFCLVEFKLQEVK---------NGPRKLDIIGFYRVQEFSQWWPVNVAELRQLQYAVAA---EVP-----NVVVGRIVTIAGEARS--ERAIVQVA-VSVLDRWHDQAPT---LFHVLTTVLAGGRV-----------DNELRGRAVDGWYRTLGELQKVASG--SRSTGAP-IPLKGLETFIDYLKANSG------SST-DFDS----FTSSVRSLRRLCQAHAES----AKSDESYEEW----RKEILQLLSTIQGLSDRLLLPQAEA---------------------------------- WP_157213968.1 MVTERKVAL-----------------------IDSACIDNSLAPQE--------------GLVGGRGMS---LILFLTDLHLGHDGA-ARPADDR-KVR-VVSDAERTSIRELAEEHIRRLSASIRQQGKEISALVLGGDITVRGQ-----------------LGGF-AELDGFLRTALG-DLLPPP--D-RIVATPGNHDVAWYET------------DARARYKHFLSYC--VKA-GYVTPPLDGIDLGPAA-----PVFTPGRHVLV----DSEGWFIAPLNSSHWSGTRAPLLDNFGN-----------DLPESAIDGLRSALSGDALNAELIEQLLKFRQFDMSRVSKDQINAFQKTIAFARTAVGD----VNDALPLVAMHHQLSP-----------VGEREEIKPFESLSNLGQVRAVFEENGIAVTMHGHKHDLLTMWSTTEHGSVDGRGVRKHEMLVVSGGTIGGGGV---PDSGRLATVVEISRK-----LRGHEITVRSVADFIAKRPAETRGYFLSGRRFEPLG-----------ARGGHIEATTFSDGYARLVAEGEATKG--SLVKNLSITIQ-------------DLSEV-EAPPAGYPEDAAGT-VGAL-------PLPDWFNQVTDWWQSVLVDAPR----GVFTHGRRLKLHGG--------KLDANQITKMIETLA---DRRPNNGRAIATLIDAESDLLGKLGP---APASFPAFCLLQLHIRTS----------GSDTFLDATAYFRKQEMRYWWPVNIAEIKRVMVTVSD---ALK-----DVKLGSITTTAAIAVW--QTTRSRVS-VPAIDRMFLQSEEGRRDLMRMAALIAQPES---------STLAPERDRLIQLWRIALEDVVPPEES---VMDSIP-VAIEGIRFLRDAVQAQHDI-----AGDPKIRSRLDDFAKLLTELEERGSRLWNM--GRETKPTNYQKKLSSEVKGMHDARGQLAELVEKLADLGTLA---------------------------------- WP_134652746.1 -------------------------------------------------------------------MA-KALILHVTDPHFFEVEA-SPLIHDH-KVT-V-TGLKQDSRQEIFGLTLELLSKRLQERKETLDAVIFTGDAQDRNS-----------------AGGH-QELREQLLKHLA-ICGVRR--D-NIVATPGNHDVNRELP-----------VDDKERFKEFMKTW--RDN-GAITPWIDGEENG-----------DARKHRFE---DPDKLFEIYPLNSSHWAQTTLTPSKAVSD-LLP-------ALQKRFDKKIDPAEFEQAYNELILPQLQKLASADIARVSPEQLDFVRNLIGQQKPKV--------RPLRIVALHHHLIA-----------PSVGEEFRPFADITNLSLLRAFLRQNEIDIVVHGHKHVENLTYDYIYPNDGPL-NLEPHRMMVISGGALDIRR------GDSPLRLIRLSGM-----PGAPEVEVETIPLAVRGLNLEDG-PRLKGRVWRTNH--------TVGGGPVIITGNDIDEVYSRAVRAAHEEAQ----GGMLIVHLDLE-----GPK--TDEKAKQLPFPHNYP--DPDGEKPGA-------FGQDWVQSLVSWWQLSRSVLEE---RIPYIHGTRLERFAG----------KFNQMNRLIALLK----QNKSTSRGIATLIDPARDFTADG-----SKEDFASFCFIQFKWRSDG--------SGSRNLLDCIGYYRAQEFKHWWPINVAELRELQMQVAN---AV------DGVPGRITTIAADARAVFTRTPGQVA-VPTIDRWLDQAPE---KLASLSMMLSGIP-------------LPMEQGLARTWSEFLTDQQAAADPSNYNPEGVP-VAVDGLRMLERLISQFSS------EDE-HTTE----LRMTLRNLADQNERYEKS----SRDRADYDKW----APAAAHYVKKLQALTNRTVAPPRAPKSRTADRAESHANDASASKGGPLKPSGRPETKTR MBK6566186.1 M-----------------------------------------------------------------------RILHFSDAHFGSKDN---GFGDY-EST-H-YYIDEVTRKSDPNVILNLLKTKF--KPNQIDLIVDSGDIGWSGV-----------------KDDY-DLAIPLY-EGLM-KYFKDA----TIVIIPGNHDVQFSKI---------ESKDKQDNYLNFIKKLYGKKF-NINFPFYENED----------------RHTLVFYKHIKNKALIVGLNSA--A--------------------------------------------NIVEHMSQI------HISHKILNKINSKIKSDKIA--------NDTLKILVVHHHLLPFIEPKWQNNVSVNNVTETVDTSLIVNSARLQSWLGENKFHMVLHGHKHLFHGREDLLWHDR--LYEREQRKLLILGAGSIGVKDDSRRPSPPSFNEILVFKSQE---SEFKFSVSINRIKETS---------TNFIIEEWIKRNH-----STSTKQAVNYFEAKNVAECHEQMAFEIEPNKK----IYNFVSIIHESRFILPSTCLIHDNQASITDIQNSFYTLHPEFDISQD--------KTGW--NYAKGIRRSFTKRSK---NYNIDHGSRLFGANDVVNLVELENKRIEEYFPVFKAIQ---NLSISSTRGYVGLYNFELDVKK-------DSSALPGLTGIQFVPFEE----------NGIKRLDIVAFFRNIELSFWWVVNCYEMEQLLNYACR---KTQN----AYVPGRITFFSSIAEW--STDHSKVAFKPNIELYSKE------QIYNLVSKL-----------------EILDKSAINELKSLLKDYLVKLSEI-------N-INILMLDELNSMMKGITI------KKD------I--ISKTSNNLIKVCELLEDS----IEERDKRFEY----IEDSKVLIQKVIHEIESYLTSIEFDSTI------------------------------- RUU14173.1 MEMFVRIARRGWMFHENIL----------------SCFHESMQLAST-----------FCGHFQEITMPNSALFLHVTDAHLTSAGT-PFERDDH-KVQ-I-AGIQQDTREGALRLMLQRLSERLAKEGRLLSGILFSGDAQDKGQ-----------------PGGH-QLLLDMLLETLA-NVGATA--A-NIVAVPGNHDVLRGSQ-----------PGSPERYADFLAAW--RKA-GCVTPWLDGVDR---------SLSDGGEHRLV---APDGKWAVYPINTSNWSQVNATLPEPLQS-VWD-------KIPGAM------AFGDTEKEARLRHQLNELARYDMARVSSQQLEALRSLIETSPRPVGG------MPLRIAVLHHHLRA-----------PSLREEVKPFADVSNLEQLRSFLRDRQIAIALHGHKHEHAVQFDHIYDQN----GHGDHRTLVISGSTFEPGK------ETDSLRLIAVAGL-----PSSPSVAIEPLSVTRGGVEAKEC-APIVRRLWSGSS---------MPGSPILIQGTDIDEVYERACEAAGAEAA----NGILIVHLDLP-----------NLPGEDLPLPSSYP--LPEP-MEDA-------DRRIWLNELVAWWQLERSGLEH---RMPFVHGSRLRRYGG----------KINQIDRIIKLLK----E-KPSTRALAVLVDPFRDFTEDG-----QNEEFASFCLVEFKRRDVS---------SSQRFIDAIAFYRAQEFARWWPINVAEMRLLQQEICS---SL------GFLPGRITTIAGDART-HSRSPTQVA-MPIIDRWLDQSPE---RIYLLGNALAHCNV-----------REGRQCDAVRGWFRTLTDLEAATKE--YNADGLP-VPIEGLKHLGAYLGAIDE------QGELDLAN----FVRVLLRLARANEAYEKS----DRTRADFGRW----KEDALDLVSELRDMTVSRVGTMT------------------------------------ WP_069875347.1 --------------------------------------------------------------------M---KILQLSDIHIDSTT-------------------DIETVKTKLTKMKESILSRL--VPGEELLICICGDIIDKGD-----------------STLF-ETACIIF-DYMKNDLFSTI--AVKFEFVPGNHDLCNNEF---------------ADFDNFTKRY------------------TEVQ-----YEYNDKVNSHL---RAFNGIDVLLSNSTFH------------------------------------------------------KNTKIGMLDIQGLRKLPSE-----------------NPTILVVHHTLLS-----------ENDGDT----SAIRNAYKLMEWAENNNIIAIMHGHTHGYKNI------------LIG-ETCRVIGVGPFLKEV----PDINKQFNFIETSEG-----------RIDKVTNYRYSADLDM---------FTRHD-------VFIGERCNTFTSSSVKDLYDTIVRETKHYKS----IYNLKVTLS------------SEFNSFEKEIQTYFSDII----------------------PVACDWQSQS--VPE---SLYYNHGKYM------------QSESIWGMDYIIQELM----NKSTSSRAIIPLIDFNMVANS-------KDRFLPSLDIIQFGFAD-----------DQRSELFLTLYLRALEVKHFLKINICEAYIMAQQLKD---KIR-----SIQRINLTIVAYKAQY--KENYGCFR-KAQIDSVTES------DLTMSI-----------------------IEKDFKAVIDMLEEKIDLSET--------V-IQDHGLENLNKALLAVSN------KGK-CSRE----LYSKTEIILKKLGELKVER-EKTSDYNAIEKI----EHDVTTAIRNLINEFEKERGQ-------------------------------------- WP_183491168.1 -------------------------------------------------------------------MAKNGFILHVADPHLFEKEP-ARGFHDL-KAS-V-EGVTQDTKEETFKLTLELLDKRLAKEGIKLDAVVFTGDAQDRFS-----------------SGGH-TWLRDTLLEVFK-DRGITK--K-NIVATPGNHDVDRNLL-----------AGNPARFKEFIEVW--RNG-ESVTPWLDVTDNA----------ESSLAHRFE---NEGKTFEIYPINSSQWSQTKLKAPASIFS-MLP-------ELTKSL-TGVEPDLVKKAYDEVILPKVEELLSADIARISPDQLFYLSNLMQHSGRDE--------RRLRIVALHHHLTA-----------PNVSEEFRAFNDITDLSLLREFLRENEVDVVIHGHKHVENLTYDYVYPSDGGSLDRPPHRMMVISGGALEVAK------GASPLRLIKLSGL-----PGAPEVEVETIPLATRGLSLKRG-PSLKGRVWRENH--------AVAGGPVIIKGTDINEVYIRAVRAAQEEAR----GGMLIVHLDLP-----NTT--TEDREN-LPFPRSYP--DPDSEPSGS-------AEHAWVRDLVSWWQLPRSTLEE---RIPYIHGTRLERFAG----------RFNQIKRLTSLLR----QNKTTSRGIATLVDPTRDFTADG-----SKEDFASFCLIQFKWHVDK--------VGGRNLLDCIGYYRAQEFKHWWPINVAELRELQQQVAA---AV------DGEPGRITTIAADARAVLTRAPGQVA-VPVIDRWLDQAPE---KLAGLATLLAGASS------------IPNGTEIKTAWSEFLASQASAAETSNYNPEGVP-VAVDGLQMLARLIEEFST------DQA-DANE----LRVTLRSLAAQNERYEKS----ARNRAAYDTW----APMASYYLGKLADLTRPMMSKSEEQ-----GTESSSALAA----------------REQ 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MBR6096458.1 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MBA2765285.1 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WP_233137945.1 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WP_184998081.1 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MBA3422833.1 -------------------------------------------------------------------MT---TILHLSDLHLGPPAE-HQYLDDH-KSL-I-AGGDRRAEKHVLREALESLAED--GLFARVSAVVVSGDLTNKSC-----------------QDGF-DEFADVL-RPII-DAVGAR----NVLVVPGNHDVPWDPG-----------PGDPDRYKGFLSAT--RAH-DLVTPLLDTEDFDGAGRP--FGTLTPERHLL-----RGDDYIVVPINSSHFCWGQEPLDDEAAE-----------ALVTAG--------------ADVTDLVDRLRRHDVARVSNAQLRALLDLLRKFEPALLNPGG---ERVRVAVLHHQLLP-----------VTPNEELKSFEALSNLGAIREVLVQLGVQVVLHGHKHEGALFWDYVA-DRGDL-DRPPHRMVVAAAAAAFRP-------GLSIGRLIHIQSA-----ASARDVLIEDVHAGTARGGAPRLGPARRARLWRPRS-------VDAIGDAMVLSGESVAEVYAQLQSVFAGRSAD-QPLRDLTCAIR-------------NGDDA-GRVPDGYP--QPEG-VEDV---------QSWMSDLVRWWQLPEPQLLQ---QVTFNHGERIHRHWK------------DQVKRAAETLK----SSAHTTRAVIMLLDPWTDGE--------PEGEFPSFVLVQLQVVAR----------AERRELDCTGYFRKQEMRYWWPINVAELARVRDAVLE---HLAGDH--AASAGRLVTISGYAAA--GDRLPTVA-LAAVDRAVDQHPE---HLWAMAHELVHPGR--------------RVAEVRDLWDRYLRELDPRGDD---PSGELP-VSYRGLRDVERMLEWLGAA-------DAPIARALGNLVGLYDALHSQRRRVRAEAATVEQAQRALEQL----RQALEVHFAEL------------G----------------------------------- MBS1888293.1 -------------------------------------------------------------------MS---LILHLSDLHLGPASP-GQRDYDD-KFG-M-DPDEGETETDHLEHTLEALGRRLVESGNGLDAIVVTGDITKGNH-----------------TDGY-RAFPPLL-ELLG-DAMPAE--D-KVVVIPGNHDVDRDLQ-----------PGDRAKLARFMDAT--RPR--YSTPLVKGLDYKSDNLH--LNPGARGRPKPV---VDLGDAVVVAINSADYCWTKEQKTKT----DWD-------AVLAAYLEG-DTGDGAEETRKRAAEELKKLRTHDIPKVDKKQIDALKKRLDVAKIGDDADRD---PRLRIAAIHHPITP-----------ATDQEEIKPFEVITNLAIVRTFLYRLGFHLVLHGHKHTSYAAWDWLAPPRDDL-EIKARRAMVLGAPGRFRV-------GGIVCRLIEVSPEGEEPVAGAPRVRIVPIK----GVDAAES-MALDIDVWPKYSLAQPAFTSANPMTPWVIEAETADAAYEQVRDLALPDPG----GRPVVSVVN-------------DPAST-ADYPTNYPD-----------------KKIPRLGDLVDWWQLPRPEAVSSYSGSTFNHGERL--YGG-----------EDSVDRAVAALP--------SSKAFALLVRSGEAG---------SEAESPAFLEVQLQTRSLV---------KGRRALDVIGVYRKQDLNLWWPVNMAELARIQAKAVATANDLKHLEA-EWEPGRLSAIAMQGVH--DDVLPQMA-GTLLDRAVDLRPE---WIYRLAYLAAVPDS------------ADEDAEVLTEWGRALGDIGD------RPPKGLL-VPSVGIERLCDALDTHPAS-----TTTPEFRA----LTKSLGNLRQRARSAEDALAGKNPNGSTLDGW----ATQLKEAAGDCEKALRKAVRAALRS---------------------------------- WP_222418008.1 -------------------------------------------------------------------MASEARFLVLTDLHLAG----TLKRDEI-KSP-SIPKIENPSRIAATGELLSSIADYLRRRHLTLEAVIFAGDAQDKGS-----------------KGSH-DAAYQSIVDAFQ-EFGIDA--A-KIVSTPGNHDVLKGSP-----------PGSEERYADFASVW--REK-GCVVPWIDGLDPQ--------KPSDTVRHRLV---ADDAQWAIYPLNTSNWSQVRANVPKDLAT-IWD-------ELPKKM------AQGNGILEEQVKAALGRLLDYDMANISNDQLKLFRQTVDDTPQPTAG------SQVRLAVMHHHLRS-----------PSFRVEYKPFEGIANLEQLRSVLKETNVAAAIHGHKHEHNFRYEYVQSSD----PDFPHRIAVVSAGTFQDGA------VHDAALLLTLKGL-----PYTPEISVERIDLPRMALDLTVS-APVSLTLVGMRN---------VEGAPVIVQGSNLDELYARAVKKAKSHI-----GETLIVHYDPS-----------DTGKGSLKLPSQYP--RSNG-VTEE-------EMQNWLEDLVQWWQLERSSRDN---DFPYPHGSRLRLFGG----------KLNQIDRIVKLLD----Q-EPSSRALAVLVDPLRDFDRNG-----EDEAFPSFTMMQVRKRETL---------RHTFSIDVIGFYRAQEFSQWWPVNMAELRLLQSELAD---QL------KANLGTITTVTTDARF-KPQGPGQVA-VPVFDRWVDQSPE---KLFMLALTLSGDTR-----------GEPFQESLLREWVRSLNDIKEASSA--ADIDGLL-IPAEGLKTLVTYLSMIDR------QGE--KSP----LVQQLRSLVTANQTYQQS----RKLAAHREAW----SGSIATIVPSIIALTPVNRNR-------------------------------------- WP_025239254.1 -------------------------------------------------------------------MG---TLLHLSDLHLAGPSAGSDVIGDY-KID-AVRPGDRQRRTSVIGHTLEQLGLALTAAEVRLDAIVITGDITAQGS-----------------QDGF-DLLPAVL-ARLG-DALPPA--D-RILIVPGNHDIVRDTQ-----------PSSVERYARFITL---RTH-GYRTAYLDGVDANDAGTL---CADPPPNPYVS---AADGSFVVVGINSCDMCGVNRDTEPAVLE-SMA-------EIERLAAQ----TDSTGRAVKALYDAWTERGRIDVARVSEVQRKLCNGLANRARAAIVDSGK--APPVMIAAFHHQLRP-----------VNSDEEFTPFEGITNLGEVREWLAGNKFDILLHGHKHADRVAVDLFVPFAEGN-WGASHRLLVISAPTIGHGQ----PASNPIGRLMTIDTD----LPRTSDLTLQLVPSRSAGTPMSLS-A-LPAEQLAIGS--------DDGPRVGVLEADTADLVYDKILGALSKLGDL---PLPLVCRFH-------------DGPSA-LTIPRNYPD-SRST-ADGQTESERREWLQDWFDQTVAWWGRPT--RGP---GGPFNHGERIRLRRG---------VDPSQFESAIDSLA----SKGTTSRALMLLIDSATHFND-------GNTQFPAFALIQMFEQDG--------------KLAMIGYFRKQEMPHWWPINVAELARLQQEAIT---ELGGRGI-TLTAGTISTVTALPVT--GSSAPSVV-IPDLDRRMET-PA---TLLELIVPLYYGGA--------------GPEEMAERWNRILDDWRPNAQA---AADSDP-VPVQGFTYLVELAEACRALNGHHMANPDAGAQ----LVLLLEQLRNANAQYAAEQ-LGSNRGQRHQQW----RSIVDSLIPQLLATVNDLARGASKA--------------------------------EA MBS1881492.1 -------------------------------------------------------------------MT--PWILHLSDPHLGQ----GHKLDDD-KDQ-LEGQPDLETSQRVFERTLKTLSGFV-SKHGAPEVVVVSGDLTYRNS-----------------RTGF-ERFVKLL-TEDH-AVLPKDH-S-RIVVVPGNHDVDWDEK-----------PGAPARYADFLEAT--RDI-GCVTPLLDGVDFDPTSGK---LSGGPSTHHVQ-----TGDFLVVPFNSSNYCGVLTNQRDSKSEDEWR------KELAPLGDR-----------AEELMEEIRRGRQVDMARISRSQIEALGEYFARQGLSTDHDPD---QRLRIAVLHHQLLP-----------ISTREERKPYESLVDLGLVRETLRDYEFGLVLHGHKHESGIYWDTVTPAADQF-GGRFRRILIISSPGDFQV-------KGPTMRAILSAQA-----PSARNISVFTFGGAGANRVHPDILSEQVVPLWTGSG-------GCDVKDEATISASGAHVGYSRLRSLFSLRDT--RPQQNLVCEID-------------DPSDA-GELPPDYP----TA-MENP---------QAWFSDLVSWWQKDRSELVQ-LGLTSFNHGERIRRRWG------------DQIDRAIRILG----AREGSSRALVTLVAPRETGRYEADERSLETGSFPAFVLAEFSLSER----------DGKLLLDCVGYFRKQEMQFWWPVNLAELALLQKEVRD---GLKD----EIGIGRIVTFAAIALW--EDDLPRVA-VPILDRLLET-PG---RLMDMALSVAFPDA--------------DLEVARDDWVQTLVDLKGNGRP------QPP-RPHAGTSELHENVSRLQGV-----KPDAKLAP----IVDLLEELRDQYATYPPG--NDPPVSA---------VKVMIKRVEKLEGAVSAALGLED------------------------------------ MBD8894835.1 --------------------------------------------------------------------M---YLIQISDLHLGDCC-------------------DLKLISKKIDSFFESVQQKV--SPDEEVILCVLGDIINGGN-----------------ASAC-KDAIEII-NYIK-CKFCNYL-KFKIVAVPGNHDICADEYGN----------LSFHTFNVLCNEF---------------------D-----YFCKGDCACVK---VEFDEADLLLVNSVFH------------------------------------------------------RDYKCGYVDIDEIKKIIIT-----------------KNTFIVMHHSIFG-----------IDKFDM----SAIKDGYSILNYVEKNKISGILHGHTHGYRNV------------VIG-NDCRIVGVGSFLKQV----DDINNQCNIIHVDHN-----------GIYSIDNFFYQGDFKE---------YKSQN-------VFTQKPTEIYSGVDLSDIYAKIKSDVQKDKI----IQNFCMKVK------------FSLEEFESQVNKYFSDNI----------------------KDAYLWQSKE--LPD---NLYYNHRQFM------------QSKNKDGIDFVVDELN----AKPTSSRAVIPLIDYDRVINS-------GDGYLPSFNIVQFGFND-----------DSKTKLIITLYLRALEVNFFLKINLCELLLMAKEISE---SIR-----SVQDVDMNIYAFRAQY--KEKFGCFV-KAKIDTLSSA------DILMLI-----------------------CHSEFENIISLLKEKNDFCET--------I-VNKKGILELRSAFNAVAT------RKK-IVKR----VFSLLDHVEKSMDELECER-CKTSNYAAIAEK----ENMTQRAFCDLITLFESGELYENI-----------------------------------